Cargando…
Generation of NSE-MerCreMer Transgenic Mice with Tamoxifen Inducible Cre Activity in Neurons
To establish a genetic tool for conditional deletion or expression of gene in neurons in a temporally controlled manner, we generated a transgenic mouse (NSE-MerCreMer), which expressed a tamoxifen inducible type of Cre recombinase specifically in neurons. The tamoxifen inducible Cre recombinase (Me...
Autores principales: | Kam, Mandy Ka Man, Lee, King Yiu, Tam, Paul Kwong Hang, Lui, Vincent Chi Hang |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346737/ https://www.ncbi.nlm.nih.gov/pubmed/22586451 http://dx.doi.org/10.1371/journal.pone.0035799 |
Ejemplares similares
-
Effects of tamoxifen inducible MerCreMer on gene expression in cardiac myocytes in mice
por: Rouhi, Leila, et al.
Publicado: (2022) -
4-hydroxytamoxifen does not deteriorate cardiac function in cardiomyocyte-specific MerCreMer transgenic mice
por: Heinen, Andre, et al.
Publicado: (2021) -
A Murine Myh6(MerCreMer) Knock-In Allele Specifically Mediates Temporal Genetic Deletion in Cardiomyocytes after Tamoxifen Induction
por: Yan, Jianyun, et al.
Publicado: (2015) -
Moderate and high amounts of tamoxifen in αMHC-MerCreMer mice induce a DNA damage response, leading to heart failure and death
por: Bersell, Kevin, et al.
Publicado: (2013) -
Tamoxifen-independent Cre-activity in SMMHC-CreER(T2) mice
por: Steffensen, L.B., et al.
Publicado: (2022)