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Polymorphism rs4919510:C>G in Mature Sequence of Human MicroRNA-608 Contributes to the Risk of HER2-Positive Breast Cancer but Not Other Subtypes

BACKGROUND: A few polymorphisms are located in the mature microRNA sequences. Such polymorphisms could directly affect the binding of microRNA to hundreds of target mRNAs. It remains unknown whether rs4919510:C>G located in the mature miR-608 alters breast cancer susceptibility. METHODS: The asso...

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Detalles Bibliográficos
Autores principales: Huang, A-Ji, Yu, Ke-Da, Li, Jing, Fan, Lei, Shao, Zhi-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346742/
https://www.ncbi.nlm.nih.gov/pubmed/22586447
http://dx.doi.org/10.1371/journal.pone.0035252