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Screening Estrogenic Activities of Chemicals or Mixtures In Vivo Using Transgenic (cyp19a1b-GFP) Zebrafish Embryos

The tg(cyp19a1b-GFP) transgenic zebrafish expresses GFP (green fluorescent protein) under the control of the cyp19a1b gene, encoding brain aromatase. This gene has two major characteristics: (i) it is only expressed in radial glial progenitors in the brain of fish and (ii) it is exquisitely sensitiv...

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Detalles Bibliográficos
Autores principales: Brion, François, Le Page, Yann, Piccini, Benjamin, Cardoso, Olivier, Tong, Sok-Keng, Chung, Bon-chu, Kah, Olivier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346763/
https://www.ncbi.nlm.nih.gov/pubmed/22586461
http://dx.doi.org/10.1371/journal.pone.0036069