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Screening Estrogenic Activities of Chemicals or Mixtures In Vivo Using Transgenic (cyp19a1b-GFP) Zebrafish Embryos
The tg(cyp19a1b-GFP) transgenic zebrafish expresses GFP (green fluorescent protein) under the control of the cyp19a1b gene, encoding brain aromatase. This gene has two major characteristics: (i) it is only expressed in radial glial progenitors in the brain of fish and (ii) it is exquisitely sensitiv...
Autores principales: | Brion, François, Le Page, Yann, Piccini, Benjamin, Cardoso, Olivier, Tong, Sok-Keng, Chung, Bon-chu, Kah, Olivier |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346763/ https://www.ncbi.nlm.nih.gov/pubmed/22586461 http://dx.doi.org/10.1371/journal.pone.0036069 |
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