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3D Profile-Based Approach to Proteome-Wide Discovery of Novel Human Chemokines

Chemokines are small secreted proteins with important roles in immune responses. They consist of a conserved three-dimensional (3D) structure, so-called IL8-like chemokine fold, which is supported by disulfide bridges characteristic of this protein family. Sequence- and profile-based computational m...

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Detalles Bibliográficos
Autores principales: Tomczak, Aurelie, Sontheimer, Jana, Drechsel, David, Hausdorf, Rainer, Gentzel, Marc, Shevchenko, Andrej, Eichler, Stefanie, Fahmy, Karim, Buchholz, Frank, Pisabarro, M. Teresa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346806/
https://www.ncbi.nlm.nih.gov/pubmed/22586462
http://dx.doi.org/10.1371/journal.pone.0036151