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3D Profile-Based Approach to Proteome-Wide Discovery of Novel Human Chemokines
Chemokines are small secreted proteins with important roles in immune responses. They consist of a conserved three-dimensional (3D) structure, so-called IL8-like chemokine fold, which is supported by disulfide bridges characteristic of this protein family. Sequence- and profile-based computational m...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346806/ https://www.ncbi.nlm.nih.gov/pubmed/22586462 http://dx.doi.org/10.1371/journal.pone.0036151 |