Cargando…

Nicotinic Acetylcholine Receptor Agonists Attenuate Septic Acute Kidney Injury in Mice by Suppressing Inflammation and Proteasome Activity

Sepsis is one of the leading causes of acute kidney injury (AKI). Septic patients who develop acute kidney injury (AKI) are at increased risk of death. To date there is no effective treatment for AKI or septic AKI. Based on their anti-inflammatory properties, we examined the effects of nicotinic ace...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Prodyot K., Yeboah, Michael M., Dowling, Oonagh, Xue, Xiangying, Powell, Saul R., Al-Abed, Yousef, Metz, Christine N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346807/
https://www.ncbi.nlm.nih.gov/pubmed/22586448
http://dx.doi.org/10.1371/journal.pone.0035361