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Interleukin-7 Influences FOXP3(+)CD4(+) Regulatory T Cells Peripheral Homeostasis

Mechanisms governing peripheral CD4+ FOXP3+ regulatory T cells (Treg) survival and homeostasis are multiple suggesting tight and complex regulation of regulatory T cells homeostasis. Some specific factors, such as TGF-β, interleukin-2 (IL-2) and B7 costimulatory molecules have been identified as ess...

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Detalles Bibliográficos
Autores principales: Simonetta, Federico, Gestermann, Nicolas, Martinet, Kim Zita, Boniotto, Michele, Tissières, Pierre, Seddon, Benedict, Bourgeois, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346843/
https://www.ncbi.nlm.nih.gov/pubmed/22586481
http://dx.doi.org/10.1371/journal.pone.0036596