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Do β-Defensins and Other Antimicrobial Peptides Play a Role in Neuroimmune Function and Neurodegeneration?

It is widely accepted that the brain responds to mechanical trauma and development of most neurodegenerative diseases with an inflammatory sequelae that was once thought exclusive to systemic immunity. Mostly cationic peptides, such as the β-defensins, originally assigned an antimicrobial function a...

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Detalles Bibliográficos
Autores principales: Williams, Wesley M., Castellani, Rudy J., Weinberg, Aaron, Perry, George, Smith, Mark A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific World Journal 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346844/
https://www.ncbi.nlm.nih.gov/pubmed/22606066
http://dx.doi.org/10.1100/2012/905785