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Development and Evaluation of a Novel Pellet-Based Tablet System for Potential Colon Delivery of Budesonide

Budesonide, a potent glucocorticoid, is used for the treatment of inflammatory bowel diseases. Current available oral formulations of budesonide have low efficacy against ulcerative colitis because of the premature drug release in the upper part of the gastrointestinal tract. In this paper a pH- and...

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Detalles Bibliográficos
Autores principales: Varshosaz, Jaleh, Emami, Jaber, Tavakoli, Naser, Minaiyan, Mohsen, Rahmani, Nakisa, Dorkoosh, Farid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346988/
https://www.ncbi.nlm.nih.gov/pubmed/22577558
http://dx.doi.org/10.1155/2012/905191