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Development and Evaluation of a Novel Pellet-Based Tablet System for Potential Colon Delivery of Budesonide
Budesonide, a potent glucocorticoid, is used for the treatment of inflammatory bowel diseases. Current available oral formulations of budesonide have low efficacy against ulcerative colitis because of the premature drug release in the upper part of the gastrointestinal tract. In this paper a pH- and...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3346988/ https://www.ncbi.nlm.nih.gov/pubmed/22577558 http://dx.doi.org/10.1155/2012/905191 |