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Activation of the Dormant Secondary Metabolite Production by Introducing Gentamicin-Resistance in a Marine-Derived Penicillium purpurogenum G59

A new approach to activate silent gene clusters for dormant secondary metabolite production has been developed by introducing gentamicin-resistance to an originally inactive, marine-derived fungal strain Penicillium purpurogenum G59. Upon treatment of the G59 spores with a high concentration of gent...

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Detalles Bibliográficos
Autores principales: Chai, Yun-Jing, Cui, Cheng-Bin, Li, Chang-Wei, Wu, Chang-Jing, Tian, Cong-Kui, Hua, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347015/
https://www.ncbi.nlm.nih.gov/pubmed/22611354
http://dx.doi.org/10.3390/md10030559