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Activation of the Dormant Secondary Metabolite Production by Introducing Gentamicin-Resistance in a Marine-Derived Penicillium purpurogenum G59
A new approach to activate silent gene clusters for dormant secondary metabolite production has been developed by introducing gentamicin-resistance to an originally inactive, marine-derived fungal strain Penicillium purpurogenum G59. Upon treatment of the G59 spores with a high concentration of gent...
Autores principales: | Chai, Yun-Jing, Cui, Cheng-Bin, Li, Chang-Wei, Wu, Chang-Jing, Tian, Cong-Kui, Hua, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347015/ https://www.ncbi.nlm.nih.gov/pubmed/22611354 http://dx.doi.org/10.3390/md10030559 |
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