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Ready, Set, Fuse! The Coronavirus Spike Protein and Acquisition of Fusion Competence

Coronavirus-cell entry programs involve virus-cell membrane fusions mediated by viral spike (S) proteins. Coronavirus S proteins acquire membrane fusion competence by receptor interactions, proteolysis, and acidification in endosomes. This review describes our current understanding of the S proteins...

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Detalles Bibliográficos
Autores principales: Heald-Sargent, Taylor, Gallagher, Tom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347323/
https://www.ncbi.nlm.nih.gov/pubmed/22590686
http://dx.doi.org/10.3390/v4040557