Deamination of 5-Methylcytosine Residues in Mammalian Cells

DNA demethylation in mammalia occurs after fertilization and during embryogenesis and accompanies cell aging and cancer transformation. With the help of the primer extension reaction, MALDI MS and DNA cleavage by thymine DNA glycosylase deamination of 5-methylcytosine residues has been shown to take...

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Detalles Bibliográficos
Autores principales: Gromenko, E.V., Spirin, P.V., Kubareva, E.A., Romanova, E.A., Prassolov, V.S., Shpanchenko, O.V., Dontsova, O.A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2009
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347525/
https://www.ncbi.nlm.nih.gov/pubmed/22649624

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347525/
https://www.ncbi.nlm.nih.gov/pubmed/22649624

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