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Deamination of 5-Methylcytosine Residues in Mammalian Cells
DNA demethylation in mammalia occurs after fertilization and during embryogenesis and accompanies cell aging and cancer transformation. With the help of the primer extension reaction, MALDI MS and DNA cleavage by thymine DNA glycosylase deamination of 5-methylcytosine residues has been shown to take...
Autores principales: | Gromenko, E.V., Spirin, P.V., Kubareva, E.A., Romanova, E.A., Prassolov, V.S., Shpanchenko, O.V., Dontsova, O.A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
A.I. Gordeyev
2009
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347525/ https://www.ncbi.nlm.nih.gov/pubmed/22649624 |
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