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An Efficient Method for the Delivery of the Interleukin-2 Gene to Human Hematopoietic Cells using the 
Fiber-Modified Recombinant Adenovirus

Recombinant human adenovirus serotype 5 (Ad5/35F-IL2) with modified fibres containing the C-terminal domain fiber-knob of human adenovirus serotype 35, carrying the gene of recombinant human IL-2, has been designed. As a result of the fiber modification, the adenovirus can efficiently deliver the ge...

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Detalles Bibliográficos
Autores principales: Rogozhin, V.N., Logunov, D.Yu., Shchebliakov, D.V., Shmarov, M.M., Khodunova, E.E., Galtseva, 
I.V., Belousova, R.V., Naroditsky, B.S., Gintsburg, A.L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347609/
https://www.ncbi.nlm.nih.gov/pubmed/22649700