Transcription Factor DLX5 As a New Target for Promising Antitumor Agents

The crystal structure of the human transcription factor DLX5 has been used for the screening of a library consisting of 10(6 )compounds by the molecular docking technique.In vitro testsof the 14 top-rated ligands showed that compound Q12 displays the best ability to inhibit the proliferation ofDlx5...

Descripción completa

Detalles Bibliográficos
Autores principales: Timakhov, R.A., Fedichev, P.O., Vinnik, A.A., Testa, J.R., Favorova, O.O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A.I. Gordeyev 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347611/
https://www.ncbi.nlm.nih.gov/pubmed/22649693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347611/
https://www.ncbi.nlm.nih.gov/pubmed/22649693

Ejemplares similares