Pandemic H1N1 Influenza Infection and Vaccination in Humans Induces Cross-Protective Antibodies that Target the Hemagglutinin Stem

Most monoclonal antibodies (mAbs) generated from humans infected or vaccinated with the 2009 pandemic H1N1 (pdmH1N1) influenza virus targeted the hemagglutinin (HA) stem. These anti-HA stem mAbs mostly used IGHV1-69 and bound readily to epitopes on the conventional seasonal influenza and pdmH1N1 vac...

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Detalles Bibliográficos
Autores principales: Thomson, C. A., Wang, Y., Jackson, L. M., Olson, M., Wang, W., Liavonchanka, A., Keleta, L., Silva, V., Diederich, S., Jones, R. B., Gubbay, J., Pasick, J., Petric, M., Jean, François, Allen, V. G., Brown, E. G., Rini, J. M., Schrader, J. W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347682/
https://www.ncbi.nlm.nih.gov/pubmed/22586427
http://dx.doi.org/10.3389/fimmu.2012.00087

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347682/
https://www.ncbi.nlm.nih.gov/pubmed/22586427
http://dx.doi.org/10.3389/fimmu.2012.00087

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