Comprehensive linker-scanning mutagenesis of the hepatitis C virus E1 and E2 envelope glycoproteins reveals new structure–function relationships

Despite extensive research, many details about the structure and functions of hepatitis C virus (HCV) glycoproteins E1 and E2 are not fully understood, and their crystal structure remains to be determined. We applied linker-scanning mutagenesis to generate a panel of 34 mutants, each containing an i...

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Detalles Bibliográficos
Autores principales: Rychłowska, Małgorzata, Owsianka, Ania M., Foung, Steven K. H., Dubuisson, Jean, Bieńkowska-Szewczyk, Krystyna, Patel, Arvind H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for General Microbiology 2011
Materias:
Animal
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347801/
https://www.ncbi.nlm.nih.gov/pubmed/21697343
http://dx.doi.org/10.1099/vir.0.034314-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3347801/
https://www.ncbi.nlm.nih.gov/pubmed/21697343
http://dx.doi.org/10.1099/vir.0.034314-0

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