Loss of PPARγ expression by fibroblasts enhances dermal wound closure

BACKGROUND: Peroxisome proliferator-activated receptor (PPAR)γ may be a key regulator of connective tissue deposition and remodeling in vivo. PPARγ expression is reduced in dermal fibroblasts isolated from fibrotic areas of scleroderma patients; PPARγ agonists suppress the persistent fibrotic phenot...

Descripción completa

Detalles Bibliográficos
Autores principales: Sha, Wei, Thompson, Katherine, South, Jennifer, Baron, Murray, Leask, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348009/
https://www.ncbi.nlm.nih.gov/pubmed/22502865
http://dx.doi.org/10.1186/1755-1536-5-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348009/
https://www.ncbi.nlm.nih.gov/pubmed/22502865
http://dx.doi.org/10.1186/1755-1536-5-5

Ejemplares similares