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Notch signals in the endothelium and cancer "stem-like" cells: opportunities for cancer therapy

Anti-angiogenesis agents and the identification of cancer stem-like cells (CSC) are opening new avenues for targeted cancer therapy. Recent evidence indicates that angiogenesis regulatory pathways and developmental pathways that control CSC fate are intimately connected, and that endothelial cells a...

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Detalles Bibliográficos
Autores principales: Gu, Jian-Wei, Rizzo, Paola, Pannuti, Antonio, Golde, Todd, Osborne, Barbara, Miele, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348040/
https://www.ncbi.nlm.nih.gov/pubmed/22487493
http://dx.doi.org/10.1186/2045-824X-4-7