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Novel therapeutic strategies targeting HIV integrase

Integration of the viral genome into host cell chromatin is a pivotal and unique step in the replication cycle of retroviruses, including HIV. Inhibiting HIV replication by specifically blocking the viral integrase enzyme that mediates this step is an obvious and attractive therapeutic strategy. Aft...

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Detalles Bibliográficos
Autores principales: Quashie, Peter K, Sloan, Richard D, Wainberg, Mark A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348091/
https://www.ncbi.nlm.nih.gov/pubmed/22498430
http://dx.doi.org/10.1186/1741-7015-10-34