High Interstitial Fluid Pressure Is Associated with Low Tumour Penetration of Diagnostic Monoclonal Antibodies Applied for Molecular Imaging Purposes

The human epithelial cell adhesion molecule (EpCAM) is highly expressed in a variety of clinical tumour entities. Although an antibody against EpCAM has successfully been used as an adjuvant therapy in colon cancer, this therapy has never gained wide-spread use. We have therefore investigated the po...

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Detalles Bibliográficos
Autores principales: Heine, Markus, Freund, Barbara, Nielsen, Peter, Jung, Caroline, Reimer, Rudolph, Hohenberg, Heinrich, Zangemeister-Wittke, Uwe, Wester, Hans-Juergen, Lüers, Georg H., Schumacher, Udo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348149/
https://www.ncbi.nlm.nih.gov/pubmed/22590529
http://dx.doi.org/10.1371/journal.pone.0036258

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348149/
https://www.ncbi.nlm.nih.gov/pubmed/22590529
http://dx.doi.org/10.1371/journal.pone.0036258

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