Novel Role of NOX in Supporting Aerobic Glycolysis in Cancer Cells with Mitochondrial Dysfunction and as a Potential Target for Cancer Therapy

Elevated aerobic glycolysis in cancer cells (the Warburg effect) may be attributed to respiration injury or mitochondrial dysfunction, but the underlying mechanisms and therapeutic significance remain elusive. Here we report that induction of mitochondrial respiratory defect by tetracycline-controll...

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Detalles Bibliográficos
Autores principales: Lu, Weiqin, Hu, Yumin, Chen, Gang, Chen, Zhao, Zhang, Hui, Wang, Feng, Feng, Li, Pelicano, Helene, Wang, Hua, Keating, Michael J., Liu, Jinsong, McKeehan, Wallace, Wang, Huamin, Luo, Yongde, Huang, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348157/
https://www.ncbi.nlm.nih.gov/pubmed/22589701
http://dx.doi.org/10.1371/journal.pbio.1001326

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348157/
https://www.ncbi.nlm.nih.gov/pubmed/22589701
http://dx.doi.org/10.1371/journal.pbio.1001326

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