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Cholesterol-Independent Effects of Methyl-β-Cyclodextrin on Chemical Synapses

The cholesterol chelating agent, methyl-β-cyclodextrin (MβCD), alters synaptic function in many systems. At crayfish neuromuscular junctions, MβCD is reported to reduce excitatory junctional potentials (EJPs) by impairing impulse propagation to synaptic terminals, and to have no postsynaptic effects...

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Detalles Bibliográficos
Autores principales: Ormerod, Kiel G., Rogasevskaia, Tatiana P., Coorssen, Jens R., Mercier, A. Joffre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348160/
https://www.ncbi.nlm.nih.gov/pubmed/22590538
http://dx.doi.org/10.1371/journal.pone.0036395