NEDD8 links Cullin–Ring ubiquitin Ligase function to the p97 pathway

The AAA ATPase p97 and its UBA-UBX cofactors are thought to extract ubiquitinated proteins from membranes or protein complexes as a prelude to their degradation. However, ubiquitinated targets have not yet been identified for many cofactors, leaving their biological function unclear. Previous analys...

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Detalles Bibliográficos
Autores principales: den Besten, Willem, Verma, Rati, Kleiger, Gary, Oania, Robert S., Deshaies, Raymond J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348432/
https://www.ncbi.nlm.nih.gov/pubmed/22466964
http://dx.doi.org/10.1038/nsmb.2269

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348432/
https://www.ncbi.nlm.nih.gov/pubmed/22466964
http://dx.doi.org/10.1038/nsmb.2269

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