Clozapine Interaction with Phosphatidyl Inositol 3-Kinase (PI3K)/Insulin Signaling Pathway in Caenorhabditis elegans

Clozapine has superior and unique effects as an antipsychotic agent, but the mediators of these effects are not known. We studied behavioral and developmental effects of clozapine in Caenorhabditis elegans, as a model system to identify previously undiscovered mechanisms of drug action. Clozapine in...

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Detalles Bibliográficos
Autores principales: Karmacharya, Rakesh, Sliwoski, Gregory R., Lundy, Miriam Y., Suckow, Raymond F., Cohen, Bruce M., Buttner, Edgar A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2009
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348699/
https://www.ncbi.nlm.nih.gov/pubmed/19322168
http://dx.doi.org/10.1038/npp.2009.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348699/
https://www.ncbi.nlm.nih.gov/pubmed/19322168
http://dx.doi.org/10.1038/npp.2009.35

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