Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer

BACKGROUND: The current study was undertaken to characterize the effect of anti-metabolites on inducing CXCL8 signaling and determining whether the constitutive and/or drug-induced CXCL8 signaling in metastatic prostate cancer (CaP) cells modulates their sensitivity to this class of agent. METHODS:...

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Detalles Bibliográficos
Autores principales: Wilson, Catherine, Maxwell, Pamela J., Longley, Daniel B., Wilson, Richard H., Johnston, Patrick G., Waugh, David J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348872/
https://www.ncbi.nlm.nih.gov/pubmed/22590561
http://dx.doi.org/10.1371/journal.pone.0036545

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348872/
https://www.ncbi.nlm.nih.gov/pubmed/22590561
http://dx.doi.org/10.1371/journal.pone.0036545

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