Cargando…

Constitutive and Treatment-Induced CXCL8-Signalling Selectively Modulates the Efficacy of Anti-Metabolite Therapeutics in Metastatic Prostate Cancer

BACKGROUND: The current study was undertaken to characterize the effect of anti-metabolites on inducing CXCL8 signaling and determining whether the constitutive and/or drug-induced CXCL8 signaling in metastatic prostate cancer (CaP) cells modulates their sensitivity to this class of agent. METHODS:...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wilson, Catherine, Maxwell, Pamela J., Longley, Daniel B., Wilson, Richard H., Johnston, Patrick G., Waugh, David J. J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348872/ https://www.ncbi.nlm.nih.gov/pubmed/22590561 http://dx.doi.org/10.1371/journal.pone.0036545

Ejemplares similares

Tumor-derived CXCL8 signaling augments stroma-derived CCL2-promoted proliferation and CXCL12-mediated invasion of PTEN-deficient prostate cancer cells
por: Maxwell, Pamela J., et al.
Publicado: (2014)

Rationale and Means to Target Pro-Inflammatory Interleukin-8 (CXCL8) Signaling in Cancer
por: Campbell, Laura M., et al.
Publicado: (2013)

Inhibition of constitutive and cxc-chemokine-induced NF-κB activity potentiates ansamycin-based HSP90-inhibitor cytotoxicity in castrate-resistant prostate cancer cells
por: Seaton, A, et al.
Publicado: (2009)

The Chemokine CXCL16 is Highly and Constitutively Expressed by Human Bronchial Epithelial Cells
por: Day, Caroline, et al.
Publicado: (2009)

Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist–Treated Prostate Cancers
por: Maxwell, Pamela J., et al.
Publicado: (2022)

CXCL13, CXCL10 and CXCL8 as Potential Biomarkers for the Diagnosis of Neurosyphilis Patients
por: Wang, Cuini, et al.
Publicado: (2016)

Dexamethasone potentiates the antiangiogenic activity of docetaxel in castration-resistant prostate cancer
por: Wilson, C, et al.
Publicado: (2008)

CXCL8, CXCL9, CXCL10, and CXCL11 as biomarkers of liver injury caused by chronic hepatitis B
por: Yu, Xin, et al.
Publicado: (2022)

CXCL8, CXCL9, and CXCL10 serum levels increase in syphilitic patients with seroresistance
por: Dong, Xiaoyan, et al.
Publicado: (2021)

CXCL8 – The First Chemokine
por: Baggiolini, Marco
Publicado: (2015)

MMP-9 and CXCL8/IL-8 Are Potential Therapeutic Targets in Epidermolysis Bullosa Simplex
por: Lettner, Thomas, et al.
Publicado: (2013)

Designing CXCL8-based decoy proteins with strong anti-inflammatory activity in vivo
por: Falsone, Angelika, et al.
Publicado: (2013)

The influence of prostatic Cutibacterium acnes infection on serum levels of IL6 and CXCL8 in prostate cancer patients
por: Ugge, Henrik, et al.
Publicado: (2018)

gcProfileMakeR: An R Package for Automatic Classification of Constitutive and Non-Constitutive Metabolites
por: Perez-Sanz, Fernando, et al.
Publicado: (2021)

The Significance of CXCL1 and CXCL8 as Well as Their Specific Receptors in Colorectal Cancer
por: Łukaszewicz-Zając, Marta, et al.
Publicado: (2020)

CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications
por: Liu, Mingli, et al.
Publicado: (2011)

High Levels of CXCL8 and Low Levels of CXCL9 and CXCL10 in Women with Maternal RhD Alloimmunization
por: Schettini, Juliana Araújo de Carvalho, et al.
Publicado: (2017)

Binding of CXCL8/IL-8 to Mycobacterium tuberculosis Modulates the Innate Immune Response
por: Krupa, Agnieszka, et al.
Publicado: (2015)

A Combined CXCL10, CXCL8 and H-FABP Panel for the Staging of Human African Trypanosomiasis Patients
por: Hainard, Alexandre, et al.
Publicado: (2009)

Cytoplasmic FLIP(S) and nuclear FLIP(L) mediate resistance of castrate-resistant prostate cancer to apoptosis induced by IAP antagonists
por: McCann, Christopher, et al.
Publicado: (2018)

Interleukin-8/CXCL8 is a growth factor for human lung cancer cells
por: Zhu, Y M, et al.
Publicado: (2004)

Expression and migratory analysis of 5 human uveal melanoma cell lines for CXCL12, CXCL8, CXCL1, and HGF
por: Di Cesare, Sebastian, et al.
Publicado: (2007)

Discovery of IL-8/CXCL8 (The Story from Frederick)
por: Yoshimura, Teizo
Publicado: (2015)

The Chemokine CXCL8 in Carcinogenesis and Drug Response
por: Gales, Dominique, et al.
Publicado: (2013)

The significance of chemokine CXCL-8 in esophageal carcinoma
por: Łukaszewicz-Zając, Marta, et al.
Publicado: (2020)

CXCL8/CXCR2 signaling mediates bone marrow fibrosis and is a therapeutic target in myelofibrosis
por: Dunbar, Andrew J., et al.
Publicado: (2023)

Peptides derived from CXCL8 based on in silico analysis inhibit CXCL8 interactions with its receptor CXCR1
por: Jiang, Shinn-Jong, et al.
Publicado: (2015)

The chemokines IP-10/CXCL10 and IL-8/CXCL8 are potential novel biomarkers of warm autoimmune hemolytic anemia
por: Branch, Donald R., et al.
Publicado: (2022)

Anti-CXCL8 Autoantibody: A Potential Diagnostic Biomarker for Esophageal Squamous Cell Carcinoma
por: Chen, Huili, et al.
Publicado: (2022)

CXCL4 and CXCL10 Predict Risk of Fatal Cerebral Malaria
por: Wilson, Nana O., et al.
Publicado: (2011)

Synthetic heparan sulfate dodecasaccharides reveal single sulfation site interconverts CXCL8 and CXCL12 chemokine biology
por: Jayson, Gordon C., et al.
Publicado: (2015)

Human brain metastatic stroma attracts breast cancer cells via chemokines CXCL16 and CXCL12
por: Chung, Brile, et al.
Publicado: (2017)

Serum Methionine Metabolites Are Risk Factors for Metastatic Prostate Cancer Progression
por: Stabler, Sally, et al.
Publicado: (2011)

Spatially resolved transcriptomics reveals pro-inflammatory fibroblast involved in lymphocyte recruitment through CXCL8 and CXCL10
por: Caetano, Ana J, et al.
Publicado: (2023)

Prostaglandin F(2α)-F-prostanoid receptor regulates CXCL8 expression in endometrial adenocarcinoma cells via the calcium–calcineurin–NFAT pathway
por: Sales, Kurt J., et al.
Publicado: (2009)

In Vitro and In Vivo Assessment of PEGylated PEI for Anti-IL-8/CxCL-1 siRNA Delivery to the Lungs
por: Hibbitts, Alan J., et al.
Publicado: (2020)

Prognostic and Pathophysiologic Significance of IL-8 (CXCL8) in Biliary Atresia
por: Godbole, Nimish, et al.
Publicado: (2021)

Correction: Rational design of a peptide capture agent for CXCL8 based on a model of the CXCL8:CXCR1 complex
por: Helmer, Dorothea, et al.
Publicado: (2018)

Unbiased Phenotype-Based Screen Identifies Therapeutic Agents Selective for Metastatic Prostate Cancer
por: Chung, Ivy, et al.
Publicado: (2021)

Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies
por: Proost, Paul, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_9utf94fkimf48kt5u530gqhe60