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An Allograft Glioma Model Reveals the Dependence of Aquaporin-4 Expression on the Brain Microenvironment

Aquaporin-4 (AQP4), the main water channel of the brain, is highly expressed in animal glioma and human glioblastoma in situ. In contrast, most cultivated glioma cell lines don’t express AQP4, and primary cell cultures of human glioblastoma lose it during the first passages. Accordingly, in C6 cells...

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Detalles Bibliográficos
Autores principales: Noell, Susan, Ritz, Rainer, Wolburg-Buchholz, Karen, Wolburg, Hartwig, Fallier-Becker, Petra
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348884/
https://www.ncbi.nlm.nih.gov/pubmed/22590566
http://dx.doi.org/10.1371/journal.pone.0036555