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An Allograft Glioma Model Reveals the Dependence of Aquaporin-4 Expression on the Brain Microenvironment
Aquaporin-4 (AQP4), the main water channel of the brain, is highly expressed in animal glioma and human glioblastoma in situ. In contrast, most cultivated glioma cell lines don’t express AQP4, and primary cell cultures of human glioblastoma lose it during the first passages. Accordingly, in C6 cells...
Autores principales: | Noell, Susan, Ritz, Rainer, Wolburg-Buchholz, Karen, Wolburg, Hartwig, Fallier-Becker, Petra |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348884/ https://www.ncbi.nlm.nih.gov/pubmed/22590566 http://dx.doi.org/10.1371/journal.pone.0036555 |
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