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Selective Activation of p120(ctn)-Kaiso Signaling to Unlock Contact Inhibition of ARPE-19 Cells without Epithelial-Mesenchymal Transition

Contact-inhibition ubiquitously exists in non-transformed cells and explains the poor regenerative capacity of in vivo human retinal pigment epithelial cells (RPE) during aging, injury and diseases. RPE injury or degeneration may unlock mitotic block mediated by contact inhibition but may also promo...

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Detalles Bibliográficos
Autores principales: Chen, Hung-Chi, Zhu, Ying-Ting, Chen, Szu-Yu, Tseng, Scheffer C. G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348893/
https://www.ncbi.nlm.nih.gov/pubmed/22590627
http://dx.doi.org/10.1371/journal.pone.0036864