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Immunogenicity and Protective Capacity of a Virosomal Respiratory Syncytial Virus Vaccine Adjuvanted with Monophosphoryl Lipid A in Mice

Respiratory Syncytial Virus (RSV) is a major cause of viral brochiolitis in infants and young children and is also a significant problem in elderly and immuno-compromised adults. To date there is no efficacious and safe RSV vaccine, partially because of the outcome of a clinical trial in the 1960s w...

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Detalles Bibliográficos
Autores principales: Kamphuis, Tobias, Meijerhof, Tjarko, Stegmann, Toon, Lederhofer, Julia, Wilschut, Jan, de Haan, Aalzen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348902/
https://www.ncbi.nlm.nih.gov/pubmed/22590614
http://dx.doi.org/10.1371/journal.pone.0036812