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Immunogenicity and Protective Capacity of a Virosomal Respiratory Syncytial Virus Vaccine Adjuvanted with Monophosphoryl Lipid A in Mice
Respiratory Syncytial Virus (RSV) is a major cause of viral brochiolitis in infants and young children and is also a significant problem in elderly and immuno-compromised adults. To date there is no efficacious and safe RSV vaccine, partially because of the outcome of a clinical trial in the 1960s w...
Autores principales: | Kamphuis, Tobias, Meijerhof, Tjarko, Stegmann, Toon, Lederhofer, Julia, Wilschut, Jan, de Haan, Aalzen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348902/ https://www.ncbi.nlm.nih.gov/pubmed/22590614 http://dx.doi.org/10.1371/journal.pone.0036812 |
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