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A Functional Screen Provides Evidence for a Conserved, Regulatory, Juxtamembrane Phosphorylation Site in Guanylyl Cyclase A and B

Kinase homology domain (KHD) phosphorylation is required for activation of guanylyl cyclase (GC)-A and -B. Phosphopeptide mapping identified multiple phosphorylation sites in GC-A and GC-B, but these approaches have difficulty identifying sites in poorly detected peptides. Here, a functional screen...

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Detalles Bibliográficos
Autores principales: Yoder, Andrea R., Robinson, Jerid W., Dickey, Deborah M., Andersland, Joshua, Rose, Beth A., Stone, Matthew D., Griffin, Timothy J., Potter, Lincoln R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348905/
https://www.ncbi.nlm.nih.gov/pubmed/22590601
http://dx.doi.org/10.1371/journal.pone.0036747