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Viral Diversity and Diversification of Major Non-Structural Genes vif, vpr, vpu, tat exon 1 and rev exon 1 during Primary HIV-1 Subtype C Infection

To assess the level of intra-patient diversity and evolution of HIV-1C non-structural genes in primary infection, viral quasispecies obtained by single genome amplification (SGA) at multiple sampling timepoints up to 500 days post-seroconversion (p/s) were analyzed. The mean intra-patient diversity...

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Detalles Bibliográficos
Autores principales: Rossenkhan, Raabya, Novitsky, Vladimir, Sebunya, Theresa K., Musonda, Rosemary, Gashe, Berhanu A., Essex, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348911/
https://www.ncbi.nlm.nih.gov/pubmed/22590503
http://dx.doi.org/10.1371/journal.pone.0035491