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European American Stratification in Ovarian Cancer Case Control Data: The Utility of Genome-Wide Data for Inferring Ancestry

We investigated the ability of several principal components analysis (PCA)-based strategies to detect and control for population stratification using data from a multi-center study of epithelial ovarian cancer among women of European-American ethnicity. These include a correction based on an ancestr...

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Detalles Bibliográficos
Autores principales: Raska, Paola, Iversen, Edwin, Chen, Ann, Chen, Zhihua, Fridley, Brooke L., Permuth-Wey, Jennifer, Tsai, Ya-Yu, Vierkant, Robert A., Goode, Ellen L., Risch, Harvey, Schildkraut, Joellen M., Sellers, Thomas A., Barnholtz-Sloan, Jill
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348917/
https://www.ncbi.nlm.nih.gov/pubmed/22590501
http://dx.doi.org/10.1371/journal.pone.0035235