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Ubiquitin-Specific Protease 25 Functions in Endoplasmic Reticulum-Associated Degradation
Endoplasmic Reticulum (ER)-associated degradation (ERAD) discards abnormal proteins synthesized in the ER. Through coordinated actions of ERAD components, misfolded/anomalous proteins are recognized, ubiquitinated, extracted from the ER and ultimately delivered to the proteasome for degradation. It...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348923/ https://www.ncbi.nlm.nih.gov/pubmed/22590560 http://dx.doi.org/10.1371/journal.pone.0036542 |