Ubiquitin-Specific Protease 25 Functions in Endoplasmic Reticulum-Associated Degradation

Endoplasmic Reticulum (ER)-associated degradation (ERAD) discards abnormal proteins synthesized in the ER. Through coordinated actions of ERAD components, misfolded/anomalous proteins are recognized, ubiquitinated, extracted from the ER and ultimately delivered to the proteasome for degradation. It...

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Detalles Bibliográficos
Autores principales: Blount, Jessica R., Burr, Aaron A., Denuc, Amanda, Marfany, Gemma, Todi, Sokol V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348923/
https://www.ncbi.nlm.nih.gov/pubmed/22590560
http://dx.doi.org/10.1371/journal.pone.0036542

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