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A Genome-Wide siRNA Screen to Identify Modulators of Insulin Sensitivity and Gluconeogenesis
BACKGROUND: Hepatic insulin resistance impairs insulin’s ability to suppress hepatic glucose production (HGP) and contributes to the development of type 2 diabetes (T2D). Although the interests to discover novel genes that modulate insulin sensitivity and HGP are high, it remains challenging to have...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348929/ https://www.ncbi.nlm.nih.gov/pubmed/22590537 http://dx.doi.org/10.1371/journal.pone.0036384 |