Conditional IL-2 Gene Deletion: Consequences for T Cell Proliferation

To explore the role of interleukin-2 (IL-2) in T cell proliferation, and to circumvent the IL-2 deficiency autoimmune syndrome of conventional il2 gene deletion, mice were created to allow conditional il2 gene deletion when treated with the estrogen analog, tamoxifen (TAM) as adults. Splenocytes fro...

Descripción completa

Detalles Bibliográficos
Autores principales: Popmihajlov, Zoran, Xu, Dong, Morgan, Heather, Milligan, Zoie, Smith, Kendall A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349275/
https://www.ncbi.nlm.nih.gov/pubmed/22590468
http://dx.doi.org/10.3389/fimmu.2012.00102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349275/
https://www.ncbi.nlm.nih.gov/pubmed/22590468
http://dx.doi.org/10.3389/fimmu.2012.00102

Ejemplares similares