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Conditional IL-2 Gene Deletion: Consequences for T Cell Proliferation

To explore the role of interleukin-2 (IL-2) in T cell proliferation, and to circumvent the IL-2 deficiency autoimmune syndrome of conventional il2 gene deletion, mice were created to allow conditional il2 gene deletion when treated with the estrogen analog, tamoxifen (TAM) as adults. Splenocytes fro...

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Detalles Bibliográficos
Autores principales:	Popmihajlov, Zoran, Xu, Dong, Morgan, Heather, Milligan, Zoie, Smith, Kendall A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349275/ https://www.ncbi.nlm.nih.gov/pubmed/22590468 http://dx.doi.org/10.3389/fimmu.2012.00102

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