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Chemical Synthesis and Biological Activity of Analogues of the Lantibiotic Epilancin 15X

[Image: see text] Lantibiotics are a large family of antibacterial peptide natural products containing multiple post-translational modifications, including the thioether structures lanthionine and methyllanthionine. Efforts to probe structure–activity relationships and engineer improved pharmacologi...

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Detalles Bibliográficos
Autores principales: Knerr, Patrick J., van der Donk, Wilfred A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2012
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349288/
https://www.ncbi.nlm.nih.gov/pubmed/22524291
http://dx.doi.org/10.1021/ja302435y