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Chemical Synthesis and Biological Activity of Analogues of the Lantibiotic Epilancin 15X
[Image: see text] Lantibiotics are a large family of antibacterial peptide natural products containing multiple post-translational modifications, including the thioether structures lanthionine and methyllanthionine. Efforts to probe structure–activity relationships and engineer improved pharmacologi...
Autores principales: | Knerr, Patrick J., van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349288/ https://www.ncbi.nlm.nih.gov/pubmed/22524291 http://dx.doi.org/10.1021/ja302435y |
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