Riluzole neuroprotection in a parkinson's disease model involves suppression of reactive astrocytosis but not GLT-1 regulation

BACKGROUND: Riluzole is a neuroprotective drug used in the treatment of motor neurone disease. Recent evidence suggests that riluzole can up-regulate the expression and activity of the astrocyte glutamate transporter, GLT-1. Given that regulation of glutamate transport is predicted to be neuroprotec...

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Detalles Bibliográficos
Autores principales: Carbone, Marica, Duty, Susan, Rattray, Marcus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349538/
https://www.ncbi.nlm.nih.gov/pubmed/22480308
http://dx.doi.org/10.1186/1471-2202-13-38

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349538/
https://www.ncbi.nlm.nih.gov/pubmed/22480308
http://dx.doi.org/10.1186/1471-2202-13-38

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