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UBXN7 docks on neddylated cullin complexes using its UIM motif and causes HIF1α accumulation
BACKGROUND: The proteins from the UBA-UBX family interact with ubiquitylated proteins via their UBA domain and with p97 via their UBX domain, thereby acting as substrate-binding adaptors for the p97 ATPase. In particular, human UBXN7 (also known as UBXD7) mediates p97 interaction with the transcript...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349548/ https://www.ncbi.nlm.nih.gov/pubmed/22537386 http://dx.doi.org/10.1186/1741-7007-10-36 |