Efficient RNA interference in patients' acute lymphoblastic leukemia cells amplified as xenografts in mice

BACKGROUND: Signaling studies in cell lines are hampered by non-physiological alterations obtained in vitro. Physiologic primary tumor cells from patients with leukemia require passaging through immune-compromised mice for amplification. The aim was to enable molecular work in patients' ALL cel...

Descripción completa

Detalles Bibliográficos
Autores principales: Höfig, Ines, Ehrhardt, Harald, Jeremias, Irmela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Methodology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349556/
https://www.ncbi.nlm.nih.gov/pubmed/22448764
http://dx.doi.org/10.1186/1478-811X-10-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349556/
https://www.ncbi.nlm.nih.gov/pubmed/22448764
http://dx.doi.org/10.1186/1478-811X-10-8

Ejemplares similares