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The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases

BACKGROUND: There is strong evidence that oxidative stress is associated with the pathogenesis of chronic obstructive pulmonary disease (COPD). The transient receptor potential melastatin-2 (TRPM2) is an oxidative stress sensing channel that is expressed in a number of inflammatory cells and therefo...

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Detalles Bibliográficos
Autores principales: Hardaker, Liz, Bahra, Parmjit, de Billy, Benjamin Cochin, Freeman, Mark, Kupfer, Natalia, Wyss, Daniel, Trifilieff, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349593/
https://www.ncbi.nlm.nih.gov/pubmed/22475739
http://dx.doi.org/10.1186/1465-9921-13-30