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The ion channel transient receptor potential melastatin-2 does not play a role in inflammatory mouse models of chronic obstructive pulmonary diseases
BACKGROUND: There is strong evidence that oxidative stress is associated with the pathogenesis of chronic obstructive pulmonary disease (COPD). The transient receptor potential melastatin-2 (TRPM2) is an oxidative stress sensing channel that is expressed in a number of inflammatory cells and therefo...
Autores principales: | Hardaker, Liz, Bahra, Parmjit, de Billy, Benjamin Cochin, Freeman, Mark, Kupfer, Natalia, Wyss, Daniel, Trifilieff, Alexandre |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349593/ https://www.ncbi.nlm.nih.gov/pubmed/22475739 http://dx.doi.org/10.1186/1465-9921-13-30 |
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