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Hybrid cells derived from breast epithelial cell/breast cancer cell fusion events show a differential RAF-AKT crosstalk

BACKGROUND: The biological phenomenon of cell fusion has been linked to several characteristics of tumour progression, including an enhanced metastatogenic capacity and an enhanced drug resistance of hybrid cells. We demonstrated recently that M13SV1-EGFP-Neo breast epithelial cells exhibiting stem...

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Detalles Bibliográficos
Autores principales: Özel, Cem, Seidel, Jeanette, Meyer-Staeckling, Sönke, Brandt, Burkhard H, Niggemann, Bernd, Zänker, Kurt S, Dittmar, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349602/
https://www.ncbi.nlm.nih.gov/pubmed/22487193
http://dx.doi.org/10.1186/1478-811X-10-10