Extracellular Nucleotides Inhibit Insulin Receptor Signaling, Stimulate Autophagy and Control Lipoprotein Secretion

Hyperglycemia is associated with abnormal plasma lipoprotein metabolism and with an elevation in circulating nucleotide levels. We evaluated how extracellular nucleotides may act to perturb hepatic lipoprotein secretion. Adenosine diphosphate (ADP) (>10 µM) acts like a proteasomal inhibitor to st...

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Detalles Bibliográficos
Autores principales: Chatterjee, Cynthia, Sparks, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349634/
https://www.ncbi.nlm.nih.gov/pubmed/22590634
http://dx.doi.org/10.1371/journal.pone.0036916

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3349634/
https://www.ncbi.nlm.nih.gov/pubmed/22590634
http://dx.doi.org/10.1371/journal.pone.0036916

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